liver/biliary system
• significantly lower lipid content in the liver of 20 week old mice on a high calorie high fat diet
however, no significant difference in food consumption or weight gain is detected in mice on a high calorie high fat diet
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• display protection from high calorie high fat diet induced liver damage and inflammation
• decreased IL6 and TNF alpha levels in livers of high fat diet fed mice compared to diet matched wild-type controls
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immune system
• Kupffer cells, treated with LPS, release less TNF-alpha into media
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