mortality/aging
• die before E9.5, even with maternal dietary purine supplementation
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Allele Symbol Allele Name Allele ID |
MthfsGt(RRK291)Byg gene trap RRK291, BayGenomics MGI:4130253 |
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Summary |
3 genotypes
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♀ | phenotype observed in females |
♂ | phenotype observed in males |
N | normal phenotype |
• die before E9.5, even with maternal dietary purine supplementation
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♀ | phenotype observed in females |
♂ | phenotype observed in males |
N | normal phenotype |
• decreased folate levels in the plasma in mice on a normal chow diet compared to diet matched controls
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• decrease in de novo purine synthesis
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N |
• no difference in food intake
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N |
• no difference in weight gain
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|
♀ | phenotype observed in females |
♂ | phenotype observed in males |
N | normal phenotype |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/02/2024 MGI 6.24 |
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