About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Pdzd2Gt(S3-7A1)Sor
gene trap S3-7A1, Philippe Soriano
MGI:4130736
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Pdzd2Gt(S3-7A1)Sor/Pdzd2Gt(S3-7A1)Sor involves: 129S4/SvJaeSor MGI:4410384
hm2
 		Pdzd2Gt(S3-7A1)Sor/Pdzd2Gt(S3-7A1)Sor involves: 129S/SvEv * 129S4/SvJaeSor MGI:6719519


Genotype
MGI:4410384
hm1
Allelic
Composition		 Pdzd2Gt(S3-7A1)Sor/Pdzd2Gt(S3-7A1)Sor
Genetic
Background		 involves: 129S4/SvJaeSor
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pdzd2Gt(S3-7A1)Sor mutation (0 available); any Pdzd2 mutation (102 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
behavior/neurological phenotype ( J:154232 )
N
• mice exhibit normal acute and chronic pain behavior

nervous system
nervous system phenotype ( J:154232 )
N
• mice exhibit normal TTX-resistant currents




Genotype
MGI:6719519
hm2
Allelic
Composition		 Pdzd2Gt(S3-7A1)Sor/Pdzd2Gt(S3-7A1)Sor
Genetic
Background		 involves: 129S/SvEv * 129S4/SvJaeSor
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pdzd2Gt(S3-7A1)Sor mutation (0 available); any Pdzd2 mutation (102 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
increased insulin secretion ( J:307008 )
• basal and following low concentration glucose stimulation due to altered potassium-ATP channel
decreased circulating glucose level ( J:307008 )
• in the random-fed state
increased circulating insulin level ( J:307008 )
• slightly in the random-fed state
improved glucose tolerance ( J:307008 )
• in mice older than 1 month of age without a change in insulin tolerance

endocrine/exocrine glands
increased insulin secretion ( J:307008 )
• basal and following low concentration glucose stimulation due to altered potassium-ATP channel




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory