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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Pdzd2Gt(S3-7A1)Sor
gene trap S3-7A1, Philippe Soriano
MGI:4130736
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Pdzd2Gt(S3-7A1)Sor/Pdzd2Gt(S3-7A1)Sor involves: 129S4/SvJaeSor MGI:4410384
hm2
 		Pdzd2Gt(S3-7A1)Sor/Pdzd2Gt(S3-7A1)Sor involves: 129S/SvEv * 129S4/SvJaeSor MGI:6719519


Genotype
MGI:4410384
hm1
Allelic
Composition		 Pdzd2Gt(S3-7A1)Sor/Pdzd2Gt(S3-7A1)Sor
Genetic
Background		 involves: 129S4/SvJaeSor
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pdzd2Gt(S3-7A1)Sor mutation (0 available); any Pdzd2 mutation (102 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
behavior/neurological phenotype ( J:154232 )
N
• mice exhibit normal acute and chronic pain behavior

nervous system
nervous system phenotype ( J:154232 )
N
• mice exhibit normal TTX-resistant currents




Genotype
MGI:6719519
hm2
Allelic
Composition		 Pdzd2Gt(S3-7A1)Sor/Pdzd2Gt(S3-7A1)Sor
Genetic
Background		 involves: 129S/SvEv * 129S4/SvJaeSor
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pdzd2Gt(S3-7A1)Sor mutation (0 available); any Pdzd2 mutation (102 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
increased insulin secretion ( J:307008 )
• basal and following low concentration glucose stimulation due to altered potassium-ATP channel
decreased circulating glucose level ( J:307008 )
• in the random-fed state
increased circulating insulin level ( J:307008 )
• slightly in the random-fed state
improved glucose tolerance ( J:307008 )
• in mice older than 1 month of age without a change in insulin tolerance

endocrine/exocrine glands
increased insulin secretion ( J:307008 )
• basal and following low concentration glucose stimulation due to altered potassium-ATP channel




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory