Phenotypes associated with this allele

• Allele Symbol: Nme7^{Gt(OST31116)Lex}
• Allele Name: gene trap OST31116, Lexicon Genetics
• Allele ID: MGI:4151115
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Nme7^Gt(OST31116)Lex/Nme7^Gt(OST31116)Lex	involves: 129S5/SvEvBrd * C57BL/6Brd	MGI:4950028

Genotype
MGI:4950028

hm1

• Allelic Composition: Nme7^{Gt(OST31116)Lex}/Nme7^{Gt(OST31116)Lex}
• Genetic Background: involves: 129S5/SvEvBrd * C57BL/6Brd

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

growth/size/body

situs inversus ( J:171184 , J:185566 )

• displayed by 50% of homozygotes (J:171184)

nervous system

hydrocephaly ( J:171184 , J:185566 )

• mild to moderate in all homozygotes (J:171184)

dilated lateral ventricle ( J:171184 )

• moderate to marked

dilated third ventricle ( J:171184 )

• moderate to marked

respiratory system

abnormal respiratory motile cilium physiology ( J:171184 )

• mild nasal exudates in some mice

craniofacial

domed cranium ( J:171184 , J:185566 )

• mild or undetectable (J:171184)

behavior/neurological

behavior/neurological phenotype ( J:171184 , J:185566 )

N • level of activity is normal (J:171184)

N • normal behavior in neurological testing (J:185566)

reproductive system

reproductive system phenotype ( J:171184 )

N • both males and females are fertile

skeleton

domed cranium ( J:171184 , J:185566 )

• mild or undetectable (J:171184)

cellular

abnormal respiratory motile cilium physiology ( J:171184 )

• mild nasal exudates in some mice

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
hydrocephalus		DOID:10908	OMIM:123155 OMIM:236600 OMIM:236635 OMIM:307000 OMIM:615219	J:185566