Analysis Tools
endocrine/exocrine glands
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• in response to glucose stimulation, islets exhibit decreased ATP content and impaired increased intracellular calcium concentrations compared with wild-type cells
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• in mice fed a high fat diet for 12 weeks
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• reduced beta cell proliferation and increased apoptosis in mice fed a high fat diet for 12 weeks
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• in mice fed a high fat diet for 12 weeks
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• in mice fed a standard diet subjected to an oral glucose tolerance test
• in mice fed a high fat diet
• glucose-treated islet cells exhibit delayed and decreased insulin secretory response compared with wild-type cells
• however, Wnt signaling lessens the decrease
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homeostasis/metabolism
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• whether fed standard diet or a high fat diet, mice exhibit normal glucose lowering effect of insulin
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• in mice fed a standard diet subjected to an oral glucose tolerance test
• in mice fed a high fat diet
• glucose-treated islet cells exhibit delayed and decreased insulin secretory response compared with wild-type cells
• however, Wnt signaling lessens the decrease
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• in mice fed a standard diet subjected to an oral glucose tolerance test
• in mice fed a high fat diet
• however, intraperitoneal glucose tolerance test is normal
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cellular
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• in mice fed a high fat diet for 12 weeks
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