Analysis Tools
mortality/aging
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• all of the homozygous mutant mice died by 3 weeks of age
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digestive/alimentary system
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• necropsy shows that the 13 day-old homozygous mutants exhibit megaesophagus
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• necropsy shows that the 13 day-old homozygous mutants exhibit hypoplasia of the glandular stomach
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immune system
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• 3 of 4 mutants exhibit thymic atrophy lymphoid depletion
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muscle
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• 3 of 4 mutants exhibit muscle degeneration
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hematopoietic system
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• 3 of 4 mutants exhibit thymic atrophy lymphoid depletion
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endocrine/exocrine glands
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• 3 of 4 mutants exhibit thymic atrophy lymphoid depletion
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growth/size/body
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• necropsy shows that the 13 day-old homozygous mutants exhibit megaesophagus
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