Phenotypes associated with this allele

• Allele Symbol: Atg4b^{Gt(OST264114)Lex}
• Allele Name: gene trap OST264114, Lexicon Genetics
• Allele ID: MGI:4256475
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Atg4b^Gt(OST264114)Lex/Atg4b^Gt(OST264114)Lex	involves: 129S5/SvEvBrd * C57BL/6J	MGI:5431383

Genotype
MGI:5431383

hm1

• Allelic Composition: Atg4b^{Gt(OST264114)Lex}/Atg4b^{Gt(OST264114)Lex}
• Genetic Background: involves: 129S5/SvEvBrd * C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

preweaning lethality, incomplete penetrance ( J:186046 )

• slightly fewer mice are produced from crosses of heterozygotes

behavior/neurological

abnormal motor learning ( J:186046 )

• impaired motor learning on a rotarod

impaired coordination ( J:186046 )

• mildly on a rotarod

nervous system

nervous system phenotype ( J:186046 )

N • mice do not exhibit neuron necrosis or degeneration

abnormal cerebellum deep nucleus morphology ( J:186046 )

• mice exhibit abnormal spheroid-like structures or bodies in the neuropil of the deep cerebellar nuclei and vestibular nuclei