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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Prpf3Gt(RRO284)Byg
gene trap RRO284, BayGenomics
MGI:4329457
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Prpf3Gt(RRO284)Byg/Prpf3Gt(RRO284)Byg involves: 129P2/OlaHsd * C57BL/6 MGI:3820246
ht2
 		Prpf3Gt(RRO284)Byg/Prpf3+ involves: 129P2/OlaHsd * C57BL/6 MGI:3820247


Genotype
MGI:3820246
hm1
Allelic
Composition		 Prpf3Gt(RRO284)Byg/Prpf3Gt(RRO284)Byg
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Prpf3Gt(RRO284)Byg mutation (0 available); any Prpf3 mutation (35 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging




Genotype
MGI:3820247
ht2
Allelic
Composition		 Prpf3Gt(RRO284)Byg/Prpf3+
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Prpf3Gt(RRO284)Byg mutation (0 available); any Prpf3 mutation (35 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
vision/eye
vision/eye phenotype ( J:141780 )
N
• despite involvement of PRPF3 mutations in retinitis pigmentosa in humans, retinal function, morphology and ultrastructure are similar to controls

Mouse Models of Human Disease
 DO ID OMIM ID(s) Ref(s)
NOT retinitis pigmentosa 18 DOID:0110356 OMIM:601414
 J:141780




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory