Phenotypes associated with this allele

• Allele Symbol: Taok3^{Gt(RRK451)Byg}
• Allele Name: gene trap RRK451, BayGenomics
• Allele ID: MGI:4329673
• Summary: 3 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Taok3^Gt(RRK451)Byg/Taok3^Gt(RRK451)Byg	B6.129P2-Taok3^Gt(RRK451)Byg	MGI:7311619
ht2	Taok3^Gt(RRK451)Byg/Taok3^+	B6.129P2-Taok3^Gt(RRK451)Byg	MGI:7311620
ht3	Taok3^Gt(RRK451)Byg/Taok3^+	(B6.129P2-Taok3^Gt(RRK451)Byg x 129/SvJ)F1	MGI:7311622

Genotype
MGI:7311619

hm1

• Allelic Composition: Taok3^{Gt(RRK451)Byg}/Taok3^{Gt(RRK451)Byg}
• Genetic Background: B6.129P2-Taok3^{Gt(RRK451)Byg}

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality, complete penetrance ( J:195683 )

• no mice are recovered

Genotype
MGI:7311620

ht2

• Allelic Composition: Taok3^{Gt(RRK451)Byg}/Taok3⁺
• Genetic Background: B6.129P2-Taok3^{Gt(RRK451)Byg}

behavior/neurological

impaired behavioral response to alcohol ( J:195683 )

• ethanol-exposed mice exhibit decreased recovery time compared with similarly treated wild-type mice

• however, mice exhibit normal ethanol consumption and pharmacokinetics

improved righting response ( J:195683 )

• ethanol-exposed mice exhibit decreased recovery time compared with similarly treated wild-type mice

• however, ethanol pharmacokinetics are normal

Genotype
MGI:7311622

ht3

• Allelic Composition: Taok3^{Gt(RRK451)Byg}/Taok3⁺
• Genetic Background: (B6.129P2-Taok3^{Gt(RRK451)Byg} x 129/SvJ)F1

behavior/neurological

behavior/neurological phenotype ( J:195683 )

N • mice exhibit normal ethanol-induced hyperactivity