All Phenotypes Nckap1<Gt(RRQ139)Byg> MGI Mouse

About Help FAQ

Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Nckap1^{Gt(RRQ139)Byg}
gene trap RRQ139, BayGenomics
MGI:4330168

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Nckap1^{Gt(RRQ139)Byg}/Nckap1^{Gt(RRQ139)Byg}	involves: 129P2/OlaHsd * C3H	MGI:5050116

Allelic Composition	Nckap1^{Gt(RRQ139)Byg}/Nckap1^{Gt(RRQ139)Byg}
Genetic Background	involves: 129P2/OlaHsd * C3H

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nckap1^{Gt(RRQ139)Byg} mutation (0 available); any Nckap1 mutation (72 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

embryo

abnormal anterior visceral endoderm cell migration ( J:166095 )

• expression analysis indicates anterior visceral endoderm cells fail to migrate from the distal tip to the embryonic-extraembryonic boundary by E6.5

cellular

increased apoptosis ( J:173526 )

• slightly increased at E7.5 with apoptotic cells scattered in a 3 germ layers

abnormal cell migration ( J:173526 )

• defect in formation of lamellipodia in cultured cells

abnormal anterior visceral endoderm cell migration ( J:166095 )

• expression analysis indicates anterior visceral endoderm cells fail to migrate from the distal tip to the embryonic-extraembryonic boundary by E6.5

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24