All Phenotypes Rps6ka6<Gt(RRS057)Byg> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Rps6ka6^{Gt(RRS057)Byg}
gene trap RRS057, BayGenomics
MGI:4330363

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
ot1	Rps6ka6^{Gt(RRS057)Byg}/Y	chimera involves: 129P2/OlaHsd	MGI:4457282

Allelic Composition	Rps6ka6^{Gt(RRS057)Byg}/Y
Genetic Background	chimera involves: 129P2/OlaHsd

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rps6ka6^{Gt(RRS057)Byg} mutation (0 available); any Rps6ka6 mutation (14 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

E8.5 Rps6ka6^{Gt(RRS057)Byg}/Y chimera exhibits impaired embryo turning, posterior truncation, and microcephaly

embryo

abnormal gastrulation ( J:160967 )

• possibly a gastrulation defect at E7.5

failure of initiation of embryo turning ( J:160967 )

• by E9.5

caudal body truncation ( J:160967 )

• posterior truncation

abnormal primitive streak morphology ( J:160967 )

absent primitive node ( J:160967 )

• at E8.0

abnormal primitive streak formation ( J:160967 )

• poorly formed

failure of chorioallantoic fusion ( J:160967 )

cardiovascular system

abnormal heart development ( J:160967 )

• delayed or hypotrophic hearts

delayed heart development ( J:160967 )

growth/size/body

microcephaly ( J:160967 )

• small heads

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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