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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Chd7Gt(RRR136)Byg
gene trap RRR136, BayGenomics
MGI:4330734
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Chd7Gt(RRR136)Byg/Chd7Gt(RRR136)Byg involves: 129P2/OlaHsd * C57BL/6 MGI:4410357
ht2
Chd7Gt(RRR136)Byg/Chd7+ involves: 129P2/OlaHsd * C57BL/6 MGI:4410356


Genotype
MGI:4410357
hm1
Allelic
Composition
Chd7Gt(RRR136)Byg/Chd7Gt(RRR136)Byg
Genetic
Background
involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Chd7Gt(RRR136)Byg mutation (1 available); any Chd7 mutation (138 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging




Genotype
MGI:4410356
ht2
Allelic
Composition
Chd7Gt(RRR136)Byg/Chd7+
Genetic
Background
involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Chd7Gt(RRR136)Byg mutation (1 available); any Chd7 mutation (138 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
cardiovascular system
• in 33% of mice at E10.5
• in 29% of mice at E10.5 (18% left and 18% right)
• 7% of mice exhibit defects in the left sixth branchial arch artery unlike wild-type mice
• at E14.5, 5% of mice exhibit cervical arch or B-segment coarcation unlike wild-type mice
• 2 mice exhibit defects in the left common carotid unlike wild-type mice
• 14% of mice exhibit abnormal great vessels unlike wild-type mice

behavior/neurological

immune system
• in 11% of mice
• in 11% of mice

craniofacial
• in 33% of mice at E10.5
• in 29% of mice at E10.5 (18% left and 18% right)
• 7% of mice exhibit defects in the left sixth branchial arch artery unlike wild-type mice

embryo
• in 33% of mice at E10.5
• in 29% of mice at E10.5 (18% left and 18% right)
• 7% of mice exhibit defects in the left sixth branchial arch artery unlike wild-type mice

hematopoietic system
• in 11% of mice
• in 11% of mice

endocrine/exocrine glands
• in 11% of mice
• in 11% of mice





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/22/2024
MGI 6.24
The Jackson Laboratory