Phenotypes associated with this allele

• Allele Symbol: Kdm2b^{Gt(RRT043)Byg}
• Allele Name: gene trap RRT043, BayGenomics
• Allele ID: MGI:4332105
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Kdm2b^Gt(RRT043)Byg/Kdm2b^Gt(RRT043)Byg	B6.129P2-Kdm2b^Gt(RRT043)Byg	MGI:5784564

Genotype
MGI:5784564

hm1

• Allelic Composition: Kdm2b^{Gt(RRT043)Byg}/Kdm2b^{Gt(RRT043)Byg}
• Genetic Background: B6.129P2-Kdm2b^{Gt(RRT043)Byg}

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality during organogenesis, complete penetrance ( J:231788 , J:233372 )

• embryos do not develop past E10.5 (J:231788)

• embryonic development ceases prior to E10.5 (J:233372)

• phenotype is more severe in females (J:233372)

• most severely affected male embryos resemble least severely affected female embryos (J:233372)

embryo

decreased embryo size ( J:231788 )

open neural tube ( J:231788 )

• open and malformed anterior neural tube

kinked neural tube ( J:231788 , J:233372 )

• kinked posterior neural tube (J:231788)

abnormal somite development ( J:231788 )

cardiovascular system

abnormal heart morphology ( J:231788 )

• heart defects

growth/size/body

decreased embryo size ( J:231788 )

nervous system

open neural tube ( J:231788 )

• open and malformed anterior neural tube

kinked neural tube ( J:231788 , J:233372 )

• kinked posterior neural tube (J:231788)