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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Epb41l2Gt(AL0682)Wtsi
gene trap AL0682, Wellcome Trust Sanger Institute
MGI:4345511
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Epb41l2Gt(AL0682)Wtsi/Epb41l2Gt(AL0682)Wtsi B6.129P2-Epb41l2Gt(AL0682)Wtsi MGI:5056429
hm2
Epb41l2Gt(AL0682)Wtsi/Epb41l2Gt(AL0682)Wtsi involves: 129P2/OlaHsd * C57BL/6 MGI:5056430


Genotype
MGI:5056429
hm1
Allelic
Composition
Epb41l2Gt(AL0682)Wtsi/Epb41l2Gt(AL0682)Wtsi
Genetic
Background
B6.129P2-Epb41l2Gt(AL0682)Wtsi
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Epb41l2Gt(AL0682)Wtsi mutation (0 available); any Epb41l2 mutation (52 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
reproductive system
N
• Background Sensitivity: male mice on a congenic C57BL/6 background are fertile with normal testis weight compared with male mice on a mixed 129 and C57BL/6 background, which are infertile with decreased testis weight




Genotype
MGI:5056430
hm2
Allelic
Composition
Epb41l2Gt(AL0682)Wtsi/Epb41l2Gt(AL0682)Wtsi
Genetic
Background
involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Epb41l2Gt(AL0682)Wtsi mutation (0 available); any Epb41l2 mutation (52 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
reproductive system
• seminiferous epithelium is atrophic with reduced thickness and large number of vacuoles compared to in wild-type mice
• Background Sensitivity: on a mixed 129 and C57BL/6 background
• Background Sensitivity: on a mixed 129 and C57BL/6 background
• seminiferous tubules contains immature or degenerated spermatogenic cells unlike in wild-type mice
• Background Sensitivity: on a mixed 129 and C57BL/6 background
• Background Sensitivity: male mice on a mixed 129 and C57BL/6 background are infertile compared with male mice on a congenic C57BL/6 background, which are fertile

endocrine/exocrine glands
• seminiferous epithelium is atrophic with reduced thickness and large number of vacuoles compared to in wild-type mice
• Background Sensitivity: on a mixed 129 and C57BL/6 background
• Background Sensitivity: on a mixed 129 and C57BL/6 background

cellular
• Background Sensitivity: on a mixed 129 and C57BL/6 background





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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory