Phenotypes associated with this allele

• Allele Symbol: Tpt1^tm1.1Atel
• Allele Name: targeted mutation 1.1, Adam Telerman
• Allele ID: MGI:4353107
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Tpt1^tm1.1Atel/Tpt1^tm1.1Atel	involves: C57BL/6	MGI:4353108

Genotype
MGI:4353108

hm1

• Allelic Composition: Tpt1^tm1.1Atel/Tpt1^tm1.1Atel
• Genetic Background: involves: C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality, complete penetrance ( J:150991 )

• mice die between E6.5 and E9.5

cellular

increased embryonic tissue cell apoptosis ( J:150991 )

• in cells from E6.5 embryos

decreased cell proliferation ( J:150991 )

• cells from embryos proliferate less than cells from a wild-type embryo

growth/size/body

embryonic growth retardation ( J:150991 )

• in most embryos at E6.5 and in all embryos at E7.5

embryo

increased embryonic tissue cell apoptosis ( J:150991 )

• in cells from E6.5 embryos

embryonic growth retardation ( J:150991 )

• in most embryos at E6.5 and in all embryos at E7.5