adipose tissue
• fat mass is significantly higher than controls 4 weeks after being fed a diet high in medium-chain triglycerides
|
growth/size/body
• body weight is significantly higher than controls 4 weeks after being fed a diet high in medium-chain triglycerides
|
homeostasis/metabolism
• mice contain in circulation des-acyl and acyl forms of human ghrelin
• when fed a diet high in medium-chain triglycerides, ghrelin levels are over 100-fold higher than endogenous with acyl-activation forms also significantly elevated
|
• mice fed a diet high in medium-chain triglycerides have less energy expenditure than diet-matched controls
• gene expression analysis suggests decreased mitochondrial fat oxidation in skeletal muscle
|