About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Afdntm2Ytk
targeted mutation 2, Yoshimi Takai
MGI:4354298
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Afdntm2Ytk/Afdntm2Ytk
Tg(Camk2a-cre)1Gsc/0 		involves: FVB/N MGI:4354299


Genotype
MGI:4354299
cn1
Allelic
Composition		 Afdntm2Ytk/Afdntm2Ytk
Tg(Camk2a-cre)1Gsc/0
Genetic
Background		 involves: FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Afdntm2Ytk mutation (0 available); any Afdn mutation (84 available)
Tg(Camk2a-cre)1Gsc mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal synapse morphology ( J:151436 )
• the number of puncta adherentia junctions per bouton is decreased compared to in wild-type mice
• the number of perforated synapses is increased compared to in wild-type mice
• however, the number of postsynaptic densities per bouton is normal




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory