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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Pgap1tm1Asp
targeted mutation 1, Andrew S Peterson
MGI:4355040
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Pgap1tm1Asp/Pgap1tm1Asp involves: 129 * C57BL/6J MGI:4355060
ht2
 		Pgap1oto/Pgap1tm1Asp involves: 129 * C57BL/6J * STOCK In(1)1Rk/J MGI:4355062


Genotype
MGI:4355060
hm1
Allelic
Composition		 Pgap1tm1Asp/Pgap1tm1Asp
Genetic
Background		 involves: 129 * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pgap1tm1Asp mutation (0 available); any Pgap1 mutation (53 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype

Forebrain defects in Pgap1oto/Pgap1oto, Pgap1oto/Pgap1tm1Asp, and Pgap1tm1Asp/Pgap1tm1Asp embryos

nervous system
abnormal forebrain morphology ( J:151594 )
• mice exhibit similar forebrain defects as observed in Pgap1oto homozygotes




Genotype
MGI:4355062
ht2
Allelic
Composition		 Pgap1oto/Pgap1tm1Asp
Genetic
Background		 involves: 129 * C57BL/6J * STOCK In(1)1Rk/J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pgap1oto mutation (0 available); any Pgap1 mutation (53 available)
Pgap1tm1Asp mutation (0 available); any Pgap1 mutation (53 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype

Forebrain defects in Pgap1oto/Pgap1oto, Pgap1oto/Pgap1tm1Asp, and Pgap1tm1Asp/Pgap1tm1Asp embryos

nervous system
abnormal forebrain morphology ( J:151594 )
• mice exhibit similar forebrain defects as observed in Pgap1oto homozygotes

vision/eye
anophthalmia ( J:151594 )
• in some mice




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory