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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tg(Thy1-EGFP)OJrs
transgene insertion O, Joshua R Sanes
MGI:4355869
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cx1
 		Srgap3tm1.1Ssod/Srgap3tm1.1Ssod
Tg(Thy1-EGFP)OJrs/0 		involves: C57BL/6J * CBA MGI:4941464
cx2
 		Srgap3tm1.1Ssod/Srgap3+
Tg(Thy1-EGFP)OJrs/0 		involves: C57BL/6J * CBA MGI:4941465


Genotype
MGI:4941464
cx1
Allelic
Composition		 Srgap3tm1.1Ssod/Srgap3tm1.1Ssod
Tg(Thy1-EGFP)OJrs/0
Genetic
Background		 involves: C57BL/6J * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Srgap3tm1.1Ssod mutation (0 available); any Srgap3 mutation (62 available)
Tg(Thy1-EGFP)OJrs mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal dendritic spine morphology ( J:169533 )
• mice exhibit reduction in spine densities in the CA1 and cortical layers IV/V compared to in wild-type mice




Genotype
MGI:4941465
cx2
Allelic
Composition		 Srgap3tm1.1Ssod/Srgap3+
Tg(Thy1-EGFP)OJrs/0
Genetic
Background		 involves: C57BL/6J * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Srgap3tm1.1Ssod mutation (0 available); any Srgap3 mutation (62 available)
Tg(Thy1-EGFP)OJrs mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal dendritic spine morphology ( J:169533 )
• the number of mushroom-shaped spines is reduced while thin spines are increased compared to in wild-type mice




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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory