All Phenotypes Prdm1<tm2.1Nutt> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Prdm1^tm2.1Nutt
targeted mutation 2.1, Stephen L Nutt
MGI:4355900

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Prdm1^tm2.1Nutt/Prdm1^tm2.1Nutt Tg(Lck-cre)1Cwi/?	involves: C57BL/6	MGI:4355904

Allelic Composition	Prdm1^tm2.1Nutt/Prdm1^tm2.1Nutt Tg(Lck-cre)1Cwi/?
Genetic Background	involves: C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Prdm1^tm2.1Nutt mutation (2 available); any Prdm1 mutation (66 available)
Tg(Lck-cre)1Cwi mutation (3 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

immune system

increased susceptibility to Orthomyxoviridae infection ( J:151858 )

• mice have some delay in recovering from an influenza infection compared to controls

• mice show pronounced lymphocytic accumulation in the tertiary lymphoid tissue after influenza infection compared to controls

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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