About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Dync2h1mmi
mei mei
MGI:4355983
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cx1
 		Dync2h1mmi/Dync2h1mmi
Kif7maki/Kif7maki
Tg(Hlxb9-GFP)1Tmj/? 		involves: C57BL/6J * FVB/N MGI:4355992
cx2
 		Dync2h1mmi/Dync2h1mmi
Tg(Hlxb9-GFP)1Tmj/? 		involves: C57BL/6J * FVB/N MGI:4355994


Genotype
MGI:4355992
cx1
Allelic
Composition		 Dync2h1mmi/Dync2h1mmi
Kif7maki/Kif7maki
Tg(Hlxb9-GFP)1Tmj/?
Genetic
Background		 involves: C57BL/6J * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dync2h1mmi mutation (0 available); any Dync2h1 mutation (215 available)
Kif7maki mutation (0 available); any Kif7 mutation (40 available)
Tg(Hlxb9-GFP)1Tmj mutation (3 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal neural tube morphology ( J:151965 )
• lack ventral neural cell types
abnormal motor neuron morphology ( J:151965 )
• have only a very small number of motor neurons at all rostrocaudal positions in the spinal cord
• loss of motor neurons is increased compared to Dync2h1 single mutants

embryo
abnormal neural tube morphology ( J:151965 )
• lack ventral neural cell types




Genotype
MGI:4355994
cx2
Allelic
Composition		 Dync2h1mmi/Dync2h1mmi
Tg(Hlxb9-GFP)1Tmj/?
Genetic
Background		 involves: C57BL/6J * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dync2h1mmi mutation (0 available); any Dync2h1 mutation (215 available)
Tg(Hlxb9-GFP)1Tmj mutation (3 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal motor neuron morphology ( J:151965 )
• lack motor neurons in the cervical spinal cord but have motor neurons that span the midline axis in more ventral regions




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory