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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Dync2h1mmi
mei mei
MGI:4355983
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cx1
 		Dync2h1mmi/Dync2h1mmi
Kif7maki/Kif7maki
Tg(Hlxb9-GFP)1Tmj/? 		involves: C57BL/6J * FVB/N MGI:4355992
cx2
 		Dync2h1mmi/Dync2h1mmi
Tg(Hlxb9-GFP)1Tmj/? 		involves: C57BL/6J * FVB/N MGI:4355994


Genotype
MGI:4355992
cx1
Allelic
Composition		 Dync2h1mmi/Dync2h1mmi
Kif7maki/Kif7maki
Tg(Hlxb9-GFP)1Tmj/?
Genetic
Background		 involves: C57BL/6J * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dync2h1mmi mutation (0 available); any Dync2h1 mutation (215 available)
Kif7maki mutation (0 available); any Kif7 mutation (39 available)
Tg(Hlxb9-GFP)1Tmj mutation (3 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal neural tube morphology ( J:151965 )
• lack ventral neural cell types
abnormal motor neuron morphology ( J:151965 )
• have only a very small number of motor neurons at all rostrocaudal positions in the spinal cord
• loss of motor neurons is increased compared to Dync2h1 single mutants

embryo
abnormal neural tube morphology ( J:151965 )
• lack ventral neural cell types




Genotype
MGI:4355994
cx2
Allelic
Composition		 Dync2h1mmi/Dync2h1mmi
Tg(Hlxb9-GFP)1Tmj/?
Genetic
Background		 involves: C57BL/6J * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dync2h1mmi mutation (0 available); any Dync2h1 mutation (215 available)
Tg(Hlxb9-GFP)1Tmj mutation (3 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal motor neuron morphology ( J:151965 )
• lack motor neurons in the cervical spinal cord but have motor neurons that span the midline axis in more ventral regions




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
06/12/2024
MGI 6.13 		The Jackson Laboratory