nervous system
• serotonergic fibers are increased in the lacunosum-moleculare (170%) and decreased in the dentate gyrus (41%) compared to in wild-type mice
|
• serotonergic fibers are decreased 41% in the dentate gyrus compared to in wild-type mice
|
• mice exhibit abnormal serotonergic fibers in the cerebral cortex, hippocampus, basal ganglia, and thalamus compared to in wild-type mice
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growth/size/body
• between 12 and 96 weeks
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behavior/neurological
• resulting in lesions
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homeostasis/metabolism
• at 10 weeks, the level of serotonin is higher in the hippocampus compared to in wild-type mice
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integument
skin lesions
(
J:151979
)
• by 36 weeks, mice develop lesions on their head, neck, and snout unlike in wild-type mice
• at 96 weeks, 50% of mice exhibit lesions on their bodies unlike wild-type mice
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