Analysis Tools
digestive/alimentary system
| N |
• when treated with doxycycline until E12.5, mice exhibit normal no ectopic mass at the pyloric-duodenum junction
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• at E16.5, mice exhibit a large mass at the pyloric junction between the stomach and duodenum unlike in control mice
• at E16.5, mice exhibit many ectopic duct-like structures unlike in control mice
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• at 6 weeks, in mice treated with doxycycline until E12.5
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• at 6 weeks, mice treated with doxycycline until E12.5 exhibit a massive expansion of ductal tissues compared to in control mice
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• at E16.5, mice exhibit hyperplastic stomach epithelium and mesenchyme
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• hyperplastic at E16.5
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endocrine/exocrine glands
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• when treated with doxycycline until E12.5, endocrine cells are replaced with ductal cells unlike in control mice
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• at 6 weeks, in mice treated with doxycycline until E12.5
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• at 6 weeks, mice treated with doxycycline until E12.5 exhibit a massive expansion of ductal tissues compared to in control mice
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• at 6 weeks, mature endocrine cells are nearly absent in mice treated with doxycycline until E12.5 unlike in control mice
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• at E10.5, the remnant of the dorsal and ventral pancreatic bud is fused to the gut tube unlike in control mice
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• at E16.5, only a pancreatic remnant remains
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liver/biliary system
| N |
• liver bud development and biliary epithelium are normal
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growth/size/body
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• at 6 weeks, mice treated with doxycycline until E12.5 exhibit a massive expansion of ductal tissues compared to in control mice
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