Phenotypes associated with this allele

• Allele Symbol: fpw
• Allele Name: fertile peewee
• Allele ID: MGI:4358376
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	fpw/fpw	involves: C3H/HeJ * C57BL/6J	MGI:4358381

Genotype
MGI:4358381

hm1

• Allelic Composition: fpw/fpw
• Genetic Background: involves: C3H/HeJ * C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

reproductive system

abnormal spermatogonia proliferation ( J:151726 )

♂ • decreased

decreased litter size ( J:151726 )

growth/size/body

postnatal growth retardation ( J:151726 )

• mice exhibit slow postnatal weight gain and lack the juvenile growth spurt observed in wild-type mice after weaning

slow postnatal weight gain ( J:151726 )

cellular

abnormal spermatogonia proliferation ( J:151726 )

♂ • decreased

decreased cell proliferation ( J:151726 )

• proliferation of hepatocytes and spermatonogia is decreased compared to in wild-type mice

decreased hepatocyte proliferation ( J:151726 )

increased cell proliferation ( J:151726 )

• proliferation of chondrocytes is increased compared to in wild-type mice

liver/biliary system

decreased hepatocyte proliferation ( J:151726 )

skeleton

abnormal skeleton physiology ( J:151726 )

• chondrocyte proliferation is increased compared to in wild-type mice

homeostasis/metabolism

decreased circulating leptin level ( J:151726 )

decreased circulating interferon-gamma level ( J:151726 )

decreased circulating interleukin-1 alpha level ( J:151726 )

increased circulating interleukin-10 level ( J:151726 )

decreased circulating interleukin-6 level ( J:151726 )

increased circulating tumor necrosis factor level ( J:151726 )

immune system

decreased circulating interferon-gamma level ( J:151726 )

decreased circulating interleukin-1 alpha level ( J:151726 )

increased circulating interleukin-10 level ( J:151726 )

decreased circulating interleukin-6 level ( J:151726 )

increased circulating tumor necrosis factor level ( J:151726 )