mortality/aging
• most homozygotes die by 21 days of age
• born in normal numbers
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Allele Symbol Allele Name Allele ID |
Apptm1.2Zhe targeted mutation 1.2, Hui Zheng MGI:4359012 |
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Summary |
2 genotypes
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♀ | phenotype observed in females |
♂ | phenotype observed in males |
N | normal phenotype |
• most homozygotes die by 21 days of age
• born in normal numbers
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♀ | phenotype observed in females |
♂ | phenotype observed in males |
N | normal phenotype |
• at E16.5, endplate band width and number are increased compared to in wild-type mice
• at P0, presynaptic and postsynaptic terminal distribution is diffuse and nerve terminal sprouting occurs unlike in wild-type mice
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/12/2024 MGI 6.24 |
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