All Phenotypes Kdm1b<tm1.1Tche> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Kdm1b^tm1.1Tche
targeted mutation 1.1, Taiping Chen
MGI:4359289

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Kdm1b^tm1.1Tche/Kdm1b^tm1.1Tche	Not Specified	MGI:4359380

Allelic Composition	Kdm1b^tm1.1Tche/Kdm1b^tm1.1Tche
Genetic Background	Not Specified

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Kdm1b^tm1.1Tche mutation (0 available); any Kdm1b mutation (63 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

reproductive system

female infertility ( J:152382 )

• heterozygous embryos of homozygous mothers die by E10.5

• normal male fertility

cellular

maternal effect ( J:152382 )

• heterozygous progeny of homozygous females show severe placental defects

• impaired embryonic growth

• neural tube defects in embryos

• pericardial edema in embryos

• loss of some but not all maternally inherited imprinting patterns

• embryos dead by E10.5

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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