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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Tg(Gpbar1)1Auw
transgene insertion 1, Johan Auwerx
MGI:4359293
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
tg1
Tg(Gpbar1)1Auw/0 involves: C57BL/6J MGI:4359384


Genotype
MGI:4359384
tg1
Allelic
Composition
Tg(Gpbar1)1Auw/0
Genetic
Background
involves: C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism
• when fed a high-fat diet, islets have higher insulin content than islets from similarly treated wild-type mice
• in response to an oral glucose load when fed a high-fat diet
• during the dark phase when fed a high-fat diet
• decreased during the dark phase when fed a high-fat diet
• compared with wild-type mice when fed a high-fat diet

endocrine/exocrine glands
• when fed a high-fat diet, pancreatic islet cells do not exhibit hypertrophy as in similarly treated wild-type mice
• when fed a high-fat diet, islets have higher insulin content than islets from similarly treated wild-type mice

behavior/neurological
• during the beginning of the dark phase regardless of diet





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/09/2024
MGI 6.24
The Jackson Laboratory