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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Cxcr3tm1Raks
targeted mutation 1, Rolf A K Stahl
MGI:4361116
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Cxcr3tm1Raks/Cxcr3tm1Raks B6.129P2-Cxcr3tm1Raks MGI:4361131


Genotype
MGI:4361131
hm1
Allelic
Composition		 Cxcr3tm1Raks/Cxcr3tm1Raks
Genetic
Background		 B6.129P2-Cxcr3tm1Raks
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cxcr3tm1Raks mutation (0 available); any Cxcr3 mutation (14 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
decreased circulating creatinine level ( J:152790 )
• in nephrotoxic nephritis-induced mice at day 14
decreased blood urea nitrogen level ( J:152790 )
• in nephrotoxic nephritis-induced mice at day 14
albuminuria ( J:152790 )
• at days 7 and 14 after nephritis induction
decreased susceptibility to injury ( J:152790 )
• at day 14, nephrotoxic nephritis-induced mice exhibit less tubulointerstitial T cell infiltrates, serum creatinine and blood urea nitrogen levels, albuminuria, renal damage, glomerular crescent formation, and glomerular sclerosis compared with similarly treated wild-type mice

renal/urinary system
albuminuria ( J:152790 )
• at days 7 and 14 after nephritis induction
kidney inflammation ( J:152790 )
• in nephrotoxic nephritis-induced mice at day 14

immune system
kidney inflammation ( J:152790 )
• in nephrotoxic nephritis-induced mice at day 14




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory