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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Hoxd13Dyc
digit in Y-shaped finger and carpe
MGI:4361275
Summary 3 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Hoxd13Dyc/Hoxd13Dyc BALB/c-Hoxd13Dyc MGI:4361288
ht2
Hoxd13Dyc/Hoxd13+ BALB/c-Hoxd13Dyc MGI:4361287
cx3
Del(2Hoxd11-Hoxd13)29Ddu/+
Hoxd13Dyc/Hoxd13+
involves: 129S2/SvPas * BALB/c MGI:4361285


Genotype
MGI:4361288
hm1
Allelic
Composition
Hoxd13Dyc/Hoxd13Dyc
Genetic
Background
BALB/c-Hoxd13Dyc
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hoxd13Dyc mutation (1 available); any Hoxd13 mutation (24 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
reproductive system

limbs/digits/tail
• at E14.5, autopod development is delayed compared to in wild-type mice
• mice exhibit defects in all of the ankle bones including metacarpal, carpal, metatarsal, and tarsal bones
• in all fingers
• mice have a sixth postaxial digit
• in digits 4 and 5
• mice exhibit defects in all of the ankle bones including metacarpal, carpal, metatarsal, and tarsal bones
• mice exhibit defects in all of the ankle bones including metacarpal, carpal, metatarsal, and tarsal bones
• mice exhibit defects in all of the ankle bones including metacarpal, carpal, metatarsal, and tarsal bones
• metatarsal bone of digit 1 is strongly deformed
• at E15.5, mice exhibit defects in metatarsus and metacarpus unlike in wild-type mice

endocrine/exocrine glands

skeleton
• mice exhibit defects in all of the ankle bones including metacarpal, carpal, metatarsal, and tarsal bones
• mice exhibit defects in all of the ankle bones including metacarpal, carpal, metatarsal, and tarsal bones
• mice exhibit defects in all of the ankle bones including metacarpal, carpal, metatarsal, and tarsal bones
• mice exhibit defects in all of the ankle bones including metacarpal, carpal, metatarsal, and tarsal bones
• metatarsal bone of digit 1 is strongly deformed
• at P0.5, ossification centers in digits are absent unlike in wild-type mice

renal/urinary system

integument




Genotype
MGI:4361287
ht2
Allelic
Composition
Hoxd13Dyc/Hoxd13+
Genetic
Background
BALB/c-Hoxd13Dyc
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hoxd13Dyc mutation (1 available); any Hoxd13 mutation (24 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
limbs/digits/tail
• in digits 2 and 5




Genotype
MGI:4361285
cx3
Allelic
Composition
Del(2Hoxd11-Hoxd13)29Ddu/+
Hoxd13Dyc/Hoxd13+
Genetic
Background
involves: 129S2/SvPas * BALB/c
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Del(2Hoxd11-Hoxd13)29Ddu mutation (2 available); any Del(2Hoxd11-Hoxd13)29Ddu mutation (2 available)
Hoxd13Dyc mutation (1 available); any Hoxd13 mutation (24 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
limbs/digits/tail
• in all digits
• in the hind limbs





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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory