reproductive system
limbs/digits/tail
• at E14.5, autopod development is delayed compared to in wild-type mice
|
• mice exhibit defects in all of the ankle bones including metacarpal, carpal, metatarsal, and tarsal bones
|
• shortened
|
• in all fingers
|
• mice have a sixth postaxial digit
|
syndactyly
(
J:153164
)
• in digits 4 and 5
|
• mice exhibit defects in all of the ankle bones including metacarpal, carpal, metatarsal, and tarsal bones
|
• mice exhibit defects in all of the ankle bones including metacarpal, carpal, metatarsal, and tarsal bones
|
• mice exhibit defects in all of the ankle bones including metacarpal, carpal, metatarsal, and tarsal bones
• metatarsal bone of digit 1 is strongly deformed
|
• at E15.5, mice exhibit defects in metatarsus and metacarpus unlike in wild-type mice
|
endocrine/exocrine glands
skeleton
• mice exhibit defects in all of the ankle bones including metacarpal, carpal, metatarsal, and tarsal bones
|
• mice exhibit defects in all of the ankle bones including metacarpal, carpal, metatarsal, and tarsal bones
|
• mice exhibit defects in all of the ankle bones including metacarpal, carpal, metatarsal, and tarsal bones
|
• mice exhibit defects in all of the ankle bones including metacarpal, carpal, metatarsal, and tarsal bones
• metatarsal bone of digit 1 is strongly deformed
|
• at P0.5, ossification centers in digits are absent unlike in wild-type mice
|
renal/urinary system
integument