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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Esr1tm2.1Gsc
targeted mutation 2.1, Gunther Schutz
MGI:4361324
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Esr1tm2.1Gsc/Esr1tm2.1Gsc involves: 129P2/OlaHsd * C57BL/6 MGI:4361329


Genotype
MGI:4361329
hm1
Allelic
Composition		 Esr1tm2.1Gsc/Esr1tm2.1Gsc
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Esr1tm2.1Gsc mutation (1 available); any Esr1 mutation (68 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
small uterus ( J:152849 )
• hypoplastic uterus

endocrine/exocrine glands
abnormal mammary gland development ( J:152849 )
• ductal mammary gland development is blunted compared to in wild-type mice

cardiovascular system

integument
abnormal mammary gland development ( J:152849 )
• ductal mammary gland development is blunted compared to in wild-type mice




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory