Phenotypes associated with this allele

• Allele Symbol: Crtam^tm1Tks
• Allele Name: targeted mutation 1, Takashi Saito
• Allele ID: MGI:4361562
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Crtam^tm1Tks/Crtam^tm1Tks	B6.Cg-Crtam^tm1Tks	MGI:4361582

Genotype
MGI:4361582

hm1

• Allelic Composition: Crtam^tm1Tks/Crtam^tm1Tks
• Genetic Background: B6.Cg-Crtam^tm1Tks

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

immune system

immune system phenotype ( J:152770 )

N • normal lymphocyte and myeloid cells development

N • normal lymphocyte distribution

abnormal response to infection ( J:152770 )

• higher viral titer (4 fold) at day 6 after infection in the lung

• decreased number (<50%) of influenza-specific CD8+ T cells in the lung

• normal Ag-specific in vivo cytotoxicity of influenza-specific CD8+ T cells