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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tg(ACTB-Abl1*I)1Spg
transgene insertion 1, Stephen P Goff
MGI:4361569
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cx1
 		Abl1tm1Mlg/Abl1tm1Mlg
Tg(ACTB-Abl1*I)1Spg/0 		involves: 129S/SvEv * C57BL/6J * CBA MGI:4361587
cx2
 		Abl1tm1Mlg/Abl1tm1Mlg
Tg(ACTB-Abl1*I)1Spg/0
Tg(ACTB-Abl1*IV)1Spg/0 		involves: 129S/SvEv * C57BL/6J * CBA MGI:4361590


Genotype
MGI:4361587
cx1
Allelic
Composition		 Abl1tm1Mlg/Abl1tm1Mlg
Tg(ACTB-Abl1*I)1Spg/0
Genetic
Background		 involves: 129S/SvEv * C57BL/6J * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Abl1tm1Mlg mutation (2 available); any Abl1 mutation (93 available)
Tg(ACTB-Abl1*I)1Spg mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
mortality/aging ( J:34643 )
N
• animals show long-term survival rates comparable to controls

hematopoietic system
decreased bone marrow cell number ( J:34643 )
• variable decreases of B lymphocyte progenitors are observed




Genotype
MGI:4361590
cx2
Allelic
Composition		 Abl1tm1Mlg/Abl1tm1Mlg
Tg(ACTB-Abl1*I)1Spg/0
Tg(ACTB-Abl1*IV)1Spg/0
Genetic
Background		 involves: 129S/SvEv * C57BL/6J * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Abl1tm1Mlg mutation (2 available); any Abl1 mutation (93 available)
Tg(ACTB-Abl1*I)1Spg mutation (0 available)
Tg(ACTB-Abl1*IV)1Spg mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
mortality/aging ( J:34643 )
N
• animals show long-term survival rates comparable to controls




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory