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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Pstpip1tm1Spg
targeted mutation 1, Stephen P Goff
MGI:4361584
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Pstpip1tm1Spg/Pstpip1tm1Spg involves: 129S/SvEv * C57BL/6 MGI:5298078


Genotype
MGI:5298078
hm1
Allelic
Composition
Pstpip1tm1Spg/Pstpip1tm1Spg
Genetic
Background
involves: 129S/SvEv * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pstpip1tm1Spg mutation (3 available); any Pstpip1 mutation (14 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
immune system
• T cells are hyperresponsive to antigen receptor stimulation
• mice exhibit various defects in immune cells

hematopoietic system
• T cells are hyperresponsive to antigen receptor stimulation





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory