Analysis Tools
nervous system
|
• occasionally, microglial cells in the neocortex and hippocampus are clustered in groups similar to the microglial nodules seen in HIV encephalitis
|
microgliosis
(
J:146427
)
|
• mice exhibit increased number of F4/80+ microglial cells that display increased branching and cytoplasmic distension, suggesting microglial activation
|
astrocytosis
(
J:146427
)
|
• widespread reactive astrocytosis
|
|
• extensive vacuolizations of dendrites
|
|
• decrease in synpato-dendritic complexity
|
|
• 40% reduction in the number of large (>100 um2) neurons in the neocortex
• loss of large pyramidal neurons
|
immune system
|
• occasionally, microglial cells in the neocortex and hippocampus are clustered in groups similar to the microglial nodules seen in HIV encephalitis
|
microgliosis
(
J:146427
)
|
• mice exhibit increased number of F4/80+ microglial cells that display increased branching and cytoplasmic distension, suggesting microglial activation
|
hematopoietic system
|
• occasionally, microglial cells in the neocortex and hippocampus are clustered in groups similar to the microglial nodules seen in HIV encephalitis
|
microgliosis
(
J:146427
)
|
• mice exhibit increased number of F4/80+ microglial cells that display increased branching and cytoplasmic distension, suggesting microglial activation
|
