Phenotypes associated with this allele

• Allele Symbol: Pah^m1Btlr
• Allele Name: mutation 1, Bruce Beutler
• Allele ID: MGI:4361841
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Pah^m1Btlr/Pah^m1Btlr	C57BL/6J-Pah^m1Btlr	MGI:4361845

Genotype
MGI:4361845

hm1

• Allelic Composition: Pah^m1Btlr/Pah^m1Btlr
• Genetic Background: C57BL/6J-Pah^m1Btlr

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

environmentally induced seizures ( J:152890 )

• homozygous mutant mice older than 6 months experience seizures after being handled

audiogenic seizures ( J:152890 )

• mice older than 6 months experience seizures if they are startled

growth/size/body

decreased body size ( J:152890 )

nervous system

environmentally induced seizures ( J:152890 )

• homozygous mutant mice older than 6 months experience seizures after being handled

audiogenic seizures ( J:152890 )

• mice older than 6 months experience seizures if they are startled

pigmentation

diluted coat color ( J:152890 )

• the fur of homozygous mutant mice is initially black, but by the time the mice are 5 weeks old it has lightened to brown

• the degree of hypopigmentation varies from mouse to mouse

vision/eye

microphthalmia ( J:152890 )

integument

diluted coat color ( J:152890 )

• the fur of homozygous mutant mice is initially black, but by the time the mice are 5 weeks old it has lightened to brown

• the degree of hypopigmentation varies from mouse to mouse