Phenotypes associated with this allele

• Allele Symbol: Dscc1^{tm1a(KOMP)Wtsi}
• Allele Name: targeted mutation 1a, Wellcome Trust Sanger Institute
• Allele ID: MGI:4362627
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Dscc1^tm1a(KOMP)Wtsi/Dscc1^tm1a(KOMP)Wtsi	B6JTyr;B6N-Dscc1^tm1a(KOMP)Wtsi/Wtsi	MGI:5781607
ht2	Dscc1^tm1a(KOMP)Wtsi/Dscc1^+	B6JTyr;B6N-Dscc1^tm1a(KOMP)Wtsi/Wtsi	MGI:5781606

Genotype
MGI:5781607

hm1

• Allelic Composition: Dscc1^{tm1a(KOMP)Wtsi}/Dscc1^{tm1a(KOMP)Wtsi}
• Genetic Background: B6JTyr;B6N-Dscc1^{tm1a(KOMP)Wtsi}/Wtsi
• Cell Lines: EPD0064_2_H09

Data Sources

IMPC Data for Dscc1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

homeostasis/metabolism

increased blood urea nitrogen level ( J:175295 )

♂

IMPC - WTSI

mortality/aging

preweaning lethality, incomplete penetrance ( J:211773 )

IMPC - WTSI

skeleton

abnormal rib morphology ( J:175295 )

♀

IMPC - WTSI

increased rib number ( J:175295 )

IMPC - WTSI

increased thoracic vertebrae number ( J:175295 )

♂

IMPC - WTSI

decreased lumbar vertebrae number ( J:175295 )

IMPC - WTSI

increased sacral vertebrae number ( J:175295 )

IMPC - WTSI

vertebral fusion ( J:175295 )

♂

IMPC - WTSI

Genotype
MGI:5781606

ht2

• Allelic Composition: Dscc1^{tm1a(KOMP)Wtsi}/Dscc1⁺
• Genetic Background: B6JTyr;B6N-Dscc1^{tm1a(KOMP)Wtsi}/Wtsi
• Cell Lines: EPD0064_2_H09

Data Sources

IMPC Data for Dscc1

behavior/neurological

abnormal behavior ( J:175295 )

IMPC - WTSI

growth/size/body

increased lean body mass ( J:175295 )

IMPC - WTSI

skeleton

increased bone mineral content ( J:175295 )

IMPC - WTSI

increased bone mineral density ( J:175295 )

IMPC - WTSI