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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Cimap2tm1a(KOMP)Wtsi
targeted mutation 1a, Wellcome Trust Sanger Institute
MGI:4362692
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Cimap2tm1a(KOMP)Wtsi/Cimap2tm1a(KOMP)Wtsi involves: C57BL/6 MGI:5694585
ht2
 		Cimap2tm1a(KOMP)Wtsi/Cimap2+ involves: C57BL/6 MGI:5694621


Genotype
MGI:5694585
hm1
Allelic
Composition		 Cimap2tm1a(KOMP)Wtsi/Cimap2tm1a(KOMP)Wtsi
Genetic
Background		 involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cimap2tm1a(KOMP)Wtsi mutation (0 available); any Cimap2 mutation (15 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging




Genotype
MGI:5694621
ht2
Allelic
Composition		 Cimap2tm1a(KOMP)Wtsi/Cimap2+
Genetic
Background		 involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cimap2tm1a(KOMP)Wtsi mutation (0 available); any Cimap2 mutation (15 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
decreased CD8-positive, alpha-beta T cell number ( J:223336 )
• decreased number of np396+ CD8+ T splenocytes after LCMV C13 infection as compared to wild type
decreased cytotoxic T cell cytolysis ( J:223336 )
• decrease in specific CTL lysis 8 days post infection with LCMV C13

immune system
decreased CD8-positive, alpha-beta T cell number ( J:223336 )
• decreased number of np396+ CD8+ T splenocytes after LCMV C13 infection as compared to wild type
decreased cytotoxic T cell cytolysis ( J:223336 )
• decrease in specific CTL lysis 8 days post infection with LCMV C13




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory