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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Strntm1a(KOMP)Wtsi
targeted mutation 1a, Wellcome Trust Sanger Institute
MGI:4363225
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Strntm1a(KOMP)Wtsi/Strntm1a(KOMP)Wtsi C57BL/6N-Strntm1a(KOMP)Wtsi MGI:5803854
ht2
 		Strntm1a(KOMP)Wtsi/Strn+ C57BL/6N-Strntm1a(KOMP)Wtsi MGI:5803855


Genotype
MGI:5803854
hm1
Allelic
Composition		 Strntm1a(KOMP)Wtsi/Strntm1a(KOMP)Wtsi
Genetic
Background		 C57BL/6N-Strntm1a(KOMP)Wtsi
Cell Lines EPD0082_3_E07
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Strntm1a(KOMP)Wtsi mutation (1 available); any Strn mutation (42 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
embryonic lethality, complete penetrance ( J:232621 )
• no mice are generated possibly due to embryonic lethality




Genotype
MGI:5803855
ht2
Allelic
Composition		 Strntm1a(KOMP)Wtsi/Strn+
Genetic
Background		 C57BL/6N-Strntm1a(KOMP)Wtsi
Cell Lines EPD0082_3_E07
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Strntm1a(KOMP)Wtsi mutation (1 available); any Strn mutation (42 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
increased systemic arterial blood pressure ( J:232621 )
• when fed a liberal salt diet

homeostasis/metabolism
increased circulating aldosterone level ( J:232621 )
• when fed a liberal salt diet




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory