Phenotypes associated with this allele

• Allele Symbol: Kmt5b^{tm1a(KOMP)Wtsi}
• Allele Name: targeted mutation 1a, Wellcome Trust Sanger Institute
• Allele ID: MGI:4363450
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Kmt5b^tm1a(KOMP)Wtsi/Kmt5b^tm1a(KOMP)Wtsi	B6JTyr;B6N-Kmt5b^tm1a(KOMP)Wtsi/Wtsi	MGI:5781773
ht2	Kmt5b^tm1a(KOMP)Wtsi/Kmt5b^+	B6JTyr;B6N-Kmt5b^tm1a(KOMP)Wtsi/Wtsi	MGI:5781772

Genotype
MGI:5781773

hm1

• Allelic Composition: Kmt5b^{tm1a(KOMP)Wtsi}/Kmt5b^{tm1a(KOMP)Wtsi}
• Genetic Background: B6JTyr;B6N-Kmt5b^{tm1a(KOMP)Wtsi}/Wtsi
• Cell Lines: EPD0022_2_D02

Data Sources

IMPC Data for Kmt5b

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

increased thermal nociceptive threshold ( J:175295 )

♀

IMPC - WTSI

growth/size/body

decreased body weight ( J:175295 )

♀

IMPC - WTSI

decreased body length ( J:175295 )

♀

IMPC - WTSI

mortality/aging

preweaning lethality, incomplete penetrance ( J:211773 )

IMPC - WTSI

Genotype
MGI:5781772

ht2

• Allelic Composition: Kmt5b^{tm1a(KOMP)Wtsi}/Kmt5b⁺
• Genetic Background: B6JTyr;B6N-Kmt5b^{tm1a(KOMP)Wtsi}/Wtsi
• Cell Lines: EPD0022_2_D02

Data Sources

IMPC Data for Kmt5b

adipose tissue

decreased total body fat amount ( J:175295 )

IMPC - WTSI

growth/size/body

decreased body weight ( J:175295 )

IMPC - WTSI

homeostasis/metabolism

decreased circulating alanine transaminase level ( J:175295 )

IMPC - WTSI

skeleton

decreased lumbar vertebrae number ( J:175295 )

♀

IMPC - WTSI

increased sacral vertebrae number ( J:175295 )

♀

IMPC - WTSI