Phenotypes associated with this allele

• Allele Symbol: Pepd^{tm1a(KOMP)Wtsi}
• Allele Name: targeted mutation 1a, Wellcome Trust Sanger Institute
• Allele ID: MGI:4363495
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Pepd^tm1a(KOMP)Wtsi/Pepd^tm1a(KOMP)Wtsi	C57BL/6N-Pepd^tm1a(KOMP)Wtsi/Ucd	MGI:5797705

Genotype
MGI:5797705

hm1

• Allelic Composition: Pepd^{tm1a(KOMP)Wtsi}/Pepd^{tm1a(KOMP)Wtsi}
• Genetic Background: C57BL/6N-Pepd^{tm1a(KOMP)Wtsi}/Ucd
• Cell Lines: EPD0224_1_C04

Data Sources

IMPC Data for Pepd

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

hematopoietic system

decreased immature B cell number ( J:211773 )

IMPC - WTSI

decreased transitional stage T1 B cell number ( J:211773 )

IMPC - WTSI

decreased mean corpuscular hemoglobin ( J:211773 )

♀

IMPC - WTSI

decreased Ly6C-positive NK T cell number ( J:211773 )

IMPC - WTSI

increased effector memory T-helper cell number ( J:211773 )

IMPC - WTSI

increased leukocyte cell number ( J:211773 )

♀

IMPC - WTSI

increased memory-marker NK cell number ( J:211773 )

IMPC - WTSI

increased CD4-positive, alpha-beta T cell number ( J:211773 )

IMPC - WTSI

increased memory CD4-positive, CD25-positive, alpha-beta regulatory T cell number ( J:211773 )

IMPC - WTSI

increased effector memory CD8-positive, alpha-beta T cell number ( J:211773 )

IMPC - WTSI

increased memory-marker CD4-negative NK T cell number ( J:211773 )

IMPC - WTSI

homeostasis/metabolism

increased circulating insulin level ( J:211773 )

♂

IMPC - WTSI

immune system

decreased immature B cell number ( J:211773 )

IMPC - WTSI

decreased transitional stage T1 B cell number ( J:211773 )

IMPC - WTSI

decreased Ly6C-positive NK T cell number ( J:211773 )

IMPC - WTSI

increased effector memory T-helper cell number ( J:211773 )

IMPC - WTSI

increased leukocyte cell number ( J:211773 )

♀

IMPC - WTSI

increased memory-marker NK cell number ( J:211773 )

IMPC - WTSI

increased CD4-positive, alpha-beta T cell number ( J:211773 )

IMPC - WTSI

increased memory CD4-positive, CD25-positive, alpha-beta regulatory T cell number ( J:211773 )

IMPC - WTSI

increased effector memory CD8-positive, alpha-beta T cell number ( J:211773 )

IMPC - WTSI

increased memory-marker CD4-negative NK T cell number ( J:211773 )

IMPC - WTSI

skeleton

abnormal bone structure ( J:211773 )

♀

IMPC - WTSI

decreased bone mineral content ( J:211773 )

♀

IMPC - WTSI

decreased bone mineral density ( J:211773 )

♀

IMPC - WTSI

abnormal joint morphology ( J:211773 )

♀

IMPC - WTSI

vision/eye

abnormal cornea morphology ( J:211773 )

IMPC - WTSI

abnormal retina morphology ( J:211773 )

♀

IMPC - WTSI