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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Nsmftm1a(KOMP)Wtsi
targeted mutation 1a, Wellcome Trust Sanger Institute
MGI:4363881
Summary 3 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Nsmftm1a(KOMP)Wtsi/Nsmftm1a(KOMP)Wtsi C57BL/6N-Nsmftm1a(KOMP)Wtsi/Wtsi MGI:5781686
hm2
Nsmftm1a(KOMP)Wtsi/Nsmftm1a(KOMP)Wtsi involves: C57BL/6N MGI:5762842
ht3
Nsmftm1a(KOMP)Wtsi/Nsmf+ involves: C57BL/6N MGI:5762843


Genotype
MGI:5781686
hm1
Allelic
Composition
Nsmftm1a(KOMP)Wtsi/Nsmftm1a(KOMP)Wtsi
Genetic
Background
C57BL/6N-Nsmftm1a(KOMP)Wtsi/Wtsi
Cell Lines EPD0136_3_G02
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nsmftm1a(KOMP)Wtsi mutation (1 available); any Nsmf mutation (18 available)
Data Sources
phenotype observed in females
phenotype observed in males
N normal phenotype
hematopoietic system




Genotype
MGI:5762842
hm2
Allelic
Composition
Nsmftm1a(KOMP)Wtsi/Nsmftm1a(KOMP)Wtsi
Genetic
Background
involves: C57BL/6N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nsmftm1a(KOMP)Wtsi mutation (1 available); any Nsmf mutation (18 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
reproductive system
N
• male mice exhibit normal puberty, reproductive organs and sex steroids
• female mice exhibit all types of follicles, including corpora lutea, and normal sex steroids and estrous cycle
• in female mice
• delayed 4 days
• smaller littler sizes and fewer litters
• female mice exhibit smaller littler sizes and fewer litters
• male mice exhibit reduced litter sizes but normal litter numbers
• reduced litter sizes but normal litter number

nervous system
N
• brain weight and morphology are normal in male and female mice
• in female, but not male, mice

endocrine/exocrine glands
• in female, but not male, mice




Genotype
MGI:5762843
ht3
Allelic
Composition
Nsmftm1a(KOMP)Wtsi/Nsmf+
Genetic
Background
involves: C57BL/6N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nsmftm1a(KOMP)Wtsi mutation (1 available); any Nsmf mutation (18 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
reproductive system
N
• male fertility is normal
• smaller littler sizes and fewer litters
• female mice exhibit smaller littler sizes and fewer litters





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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory