Phenotypes associated with this allele

• Allele Symbol: Ccdc39^{tm1a(KOMP)Wtsi}
• Allele Name: targeted mutation 1a, Wellcome Trust Sanger Institute
• Allele ID: MGI:4364215
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	Ccdc39^prh/Ccdc39^tm1a(KOMP)Wtsi	involves: A/J * C57BL/6N * FVB/N	MGI:6117326

Genotype
MGI:6117326

ht1

• Allelic Composition: Ccdc39^prh/Ccdc39^{tm1a(KOMP)Wtsi}
• Genetic Background: involves: A/J * C57BL/6N * FVB/N
• Cell Lines: EPD0228_3_H08

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

postnatal lethality, complete penetrance ( J:253968 )

• all compound heterozygotes die within 3 weeks of age, similar to Ccdc39^prh homozygotes

growth/size/body

decreased body weight ( J:253968 )

• body weight is significantly decreased at P6-P14

nervous system

hydrocephaly ( J:253968 )

• compound heteroygotes develop severe hydrocephalus by P9

enlarged brain ventricles ( J:253968 )

• at P0, compound heteroygotes exhibit mild ventriculomegaly

enlarged lateral ventricles ( J:253968 )

• lateral ventricles are significantly enlarged at P9