Phenotypes associated with this allele

• Allele Symbol: Fads3^{tm1a(KOMP)Wtsi}
• Allele Name: targeted mutation 1a, Wellcome Trust Sanger Institute
• Allele ID: MGI:4364316
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Fads3^tm1a(KOMP)Wtsi/Fads3^tm1a(KOMP)Wtsi	C57BL/6-Fads3^tm1a(KOMP)Wtsi	MGI:6158411

Genotype
MGI:6158411

hm1

• Allelic Composition: Fads3^{tm1a(KOMP)Wtsi}/Fads3^{tm1a(KOMP)Wtsi}
• Genetic Background: C57BL/6-Fads3^{tm1a(KOMP)Wtsi}

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

homeostasis/metabolism

homeostasis/metabolism phenotype ( J:256005 )

N • food intake and metabolic rate

decreased fatty acids level ( J:256005 )

• lower docosahexaenoic acid (DHA, 22:6n- 3) levels in brain at age P1 and P7

• lower arachidonic acid (AA, 20:4n-6) levels in brain at age P1

• DHA level in brain at age P3 and from P13-P30

decreased liver free fatty acids level ( J:256005 )

• lower docosahexaenoic acid (DHA, 22:6n- 3) levels in liver at age P21 and P30

• lower arachidonic acid (AA, 20:4n-6) levels in liver at age P1

increased fatty acids level ( J:256005 )

• higher linoleic acid (LA, 18:2n-6) levels in brain at age P1 and P30

increased liver free fatty acids level ( J:256005 )

• higher alpha-linolenic acid (ALA, 18:3n-3) levels in liver at age P1 and P3

• higher docosapentaenoic acid (DPA, 22:5n-3) levels in liver at age P1-P13

• higher docosahexaenoic acid (DHA, 22:6n- 3) levels in liver at age P3

• higher linoleic acid (LA, 18:2n-6) levels in liver at age P1-P13

• higher adrenic acid (ADA, 22:4n-6) levels in liver at age P1

• higher arachidonic acid (AA, 20:4n-6) levels in liver at age P30

liver/biliary system

decreased liver free fatty acids level ( J:256005 )

• lower docosahexaenoic acid (DHA, 22:6n- 3) levels in liver at age P21 and P30

• lower arachidonic acid (AA, 20:4n-6) levels in liver at age P1

increased liver free fatty acids level ( J:256005 )

• higher alpha-linolenic acid (ALA, 18:3n-3) levels in liver at age P1 and P3

• higher docosapentaenoic acid (DPA, 22:5n-3) levels in liver at age P1-P13

• higher docosahexaenoic acid (DHA, 22:6n- 3) levels in liver at age P3

• higher linoleic acid (LA, 18:2n-6) levels in liver at age P1-P13

• higher adrenic acid (ADA, 22:4n-6) levels in liver at age P1

• higher arachidonic acid (AA, 20:4n-6) levels in liver at age P30

behavior/neurological

behavior/neurological phenotype ( J:256005 )

N • food intake and physical activity

growth/size/body

growth/size/body region phenotype ( J:256005 )

N • growth rate and physical appearance

mortality/aging

mortality/aging ( J:256005 )

N • viability and longevity

reproductive system

reproductive system phenotype ( J:256005 )

N • fertility and litter size