Phenotypes associated with this allele

• Allele Symbol: Arhgef4^{tm1a(KOMP)Wtsi}
• Allele Name: targeted mutation 1a, Wellcome Trust Sanger Institute
• Allele ID: MGI:4364388
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Arhgef4^tm1a(KOMP)Wtsi/Arhgef4^tm1a(KOMP)Wtsi	C57BL/6N-Arhgef4^tm1a(KOMP)Wtsi/Wtsi	MGI:5782024

Genotype
MGI:5782024

hm1

• Allelic Composition: Arhgef4^{tm1a(KOMP)Wtsi}/Arhgef4^{tm1a(KOMP)Wtsi}
• Genetic Background: C57BL/6N-Arhgef4^{tm1a(KOMP)Wtsi}/Wtsi
• Cell Lines: EPD0135_1_A05

Data Sources

IMPC Data for Arhgef4

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

abnormal response to tactile stimuli ( J:165965 )

♂

IMPC - ICS

hematopoietic system

decreased hemoglobin content ( J:165965 )

IMPC - HMGU

increased mature B cell number ( J:165965 )

IMPC - HMGU

decreased T cell number ( J:165965 )

IMPC - HMGU

decreased IgE level ( J:165965 )

♂

IMPC - HMGU

decreased IgG1 level ( J:165965 )

IMPC - HMGU

homeostasis/metabolism

decreased circulating triglyceride level ( J:165965 )

IMPC - HMGU

increased circulating alkaline phosphatase level ( J:165965 )

♀

IMPC - HMGU

increased circulating total protein level ( J:165965 )

♀

IMPC - HMGU

immune system

increased mature B cell number ( J:165965 )

IMPC - HMGU

decreased T cell number ( J:165965 )

IMPC - HMGU

decreased IgE level ( J:165965 )

♂

IMPC - HMGU

decreased IgG1 level ( J:165965 )

IMPC - HMGU

skeleton

decreased bone mineral density ( J:165965 )

IMPC - HAR