Phenotypes associated with this allele

• Allele Symbol: Gtpbp3^{tm1a(KOMP)Wtsi}
• Allele Name: targeted mutation 1a, Wellcome Trust Sanger Institute
• Allele ID: MGI:4364401
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Gtpbp3^tm1a(KOMP)Wtsi/Gtpbp3^tm1a(KOMP)Wtsi	C57BL/6N-Gtpbp3^tm1a(KOMP)Wtsi/Wtsi	MGI:6262592

Genotype
MGI:6262592

hm1

• Allelic Composition: Gtpbp3^{tm1a(KOMP)Wtsi}/Gtpbp3^{tm1a(KOMP)Wtsi}
• Genetic Background: C57BL/6N-Gtpbp3^{tm1a(KOMP)Wtsi}/Wtsi
• Cell Lines: EPD0135_2_B03

Data Sources

IMPC Data for Gtpbp3

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

embryo

abnormal chorion morphology ( J:261316 )

• unpatterned chorion

abnormal placenta morphology ( J:261316 )

• fibrotic/acellular lesions at E9.5

abnormal trophoblast layer morphology ( J:261316 )

• small or absent trophoblast compartment

mortality/aging

preweaning lethality, incomplete penetrance ( J:211773 , J:261316 )

IMPC - WTSI (J:211773)

MGI

• fewer than the expected numbers of mice are seen at P14 (J:261316)