Phenotypes associated with this allele

• Allele Symbol: Chfr^{tm1a(KOMP)Wtsi}
• Allele Name: targeted mutation 1a, Wellcome Trust Sanger Institute
• Allele ID: MGI:4364442
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Chfr^tm1a(KOMP)Wtsi/Chfr^tm1a(KOMP)Wtsi	C57BL/6NCrl-Chfr^tm1a(KOMP)Wtsi/Ccpcz	MGI:7768307

Genotype
MGI:7768307

hm1

• Allelic Composition: Chfr^{tm1a(KOMP)Wtsi}/Chfr^{tm1a(KOMP)Wtsi}
• Genetic Background: C57BL/6NCrl-Chfr^{tm1a(KOMP)Wtsi}/Ccpcz
• Cell Lines: EPD0314_2_B01

Data Sources

IMPC Data for Chfr

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

thin ventricular wall ( J:211773 )

♀

IMPC - CCP-IMG

decreased heart rate ( J:211773 )

IMPC - CCP-IMG

endocrine/exocrine glands

abnormal testis morphology ( J:211773 )

♂

IMPC - CCP-IMG

small testis ( J:211773 )

♂

IMPC - CCP-IMG

growth/size/body

increased kidney weight ( J:211773 )

♂

IMPC - CCP-IMG

hematopoietic system

abnormal spleen morphology ( J:211773 )

♀

IMPC - CCP-IMG

homeostasis/metabolism

increased circulating alanine transaminase level ( J:211773 )

♂

IMPC - CCP-IMG

increased circulating aspartate transaminase level ( J:211773 )

♂

IMPC - CCP-IMG

immune system

abnormal spleen morphology ( J:211773 )

♀

IMPC - CCP-IMG

integument

abnormal coat/hair pigmentation ( J:211773 )

IMPC - CCP-IMG

abnormal skin morphology ( J:211773 )

♀

IMPC - CCP-IMG

abnormal skin coloration ( J:211773 )

♀

IMPC - CCP-IMG

pigmentation

abnormal coat/hair pigmentation ( J:211773 )

IMPC - CCP-IMG

renal/urinary system

increased kidney weight ( J:211773 )

♂

IMPC - CCP-IMG

reproductive system

abnormal testis morphology ( J:211773 )

♂

IMPC - CCP-IMG

small testis ( J:211773 )

♂

IMPC - CCP-IMG

respiratory system

decreased lung elastance ( J:211773 )

♂

IMPC - CCP-IMG

abnormal inspiratory capacity ( J:211773 )

♂

IMPC - CCP-IMG

increased lung compliance ( J:211773 )

♂

IMPC - CCP-IMG