Phenotypes associated with this allele

• Allele Symbol: Eif4e3^{tm1a(KOMP)Wtsi}
• Allele Name: targeted mutation 1a, Wellcome Trust Sanger Institute
• Allele ID: MGI:4364967
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Eif4e3^tm1a(KOMP)Wtsi/Eif4e3^tm1a(KOMP)Wtsi	B6JTyr;B6N-Eif4e3^tm1a(KOMP)Wtsi/Wtsi	MGI:5781618
hm2	Eif4e3^tm1a(KOMP)Wtsi/Eif4e3^tm1a(KOMP)Wtsi	involves: C57BL/6 * C57BL/6N	MGI:5790949

Genotype
MGI:5781618

hm1

• Allelic Composition: Eif4e3^{tm1a(KOMP)Wtsi}/Eif4e3^{tm1a(KOMP)Wtsi}
• Genetic Background: B6JTyr;B6N-Eif4e3^{tm1a(KOMP)Wtsi}/Wtsi
• Cell Lines: EPD0081_5_C11

Data Sources

IMPC Data for Eif4e3

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

abnormal gait ( J:175295 )

♀

IMPC - WTSI

homeostasis/metabolism

decreased circulating cholesterol level ( J:175295 )

♂

IMPC - WTSI

decreased circulating HDL cholesterol level ( J:175295 )

♂

IMPC - WTSI

decreased circulating LDL cholesterol level ( J:175295 )

♂

IMPC - WTSI

decreased circulating calcium level ( J:175295 )

♂

IMPC - WTSI

decreased circulating alanine transaminase level ( J:175295 )

IMPC - WTSI

decreased circulating aspartate transaminase level ( J:175295 )

IMPC - WTSI

decreased lactate dehydrogenase level ( J:175295 )

IMPC - WTSI

Genotype
MGI:5790949

hm2

• Allelic Composition: Eif4e3^{tm1a(KOMP)Wtsi}/Eif4e3^{tm1a(KOMP)Wtsi}
• Genetic Background: involves: C57BL/6 * C57BL/6N
• Cell Lines: EPD0081_5_C11

skeleton

decreased bone trabecula number ( J:213427 )