Phenotypes associated with this allele

• Allele Symbol: Heyl^tm1.2Abmu
• Allele Name: targeted mutation 1.2, Abhishek Mukhopadhyay
• Allele ID: MGI:4365754
• Summary: 3 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Heyl^tm1.2Abmu/Heyl^tm1.2Abmu	involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6 * FVB/N	MGI:4365768
cx2	Hey1^tm1Gess/Hey1^tm1Gess Heyl^tm1.2Abmu/Heyl^tm1.2Abmu	involves: 129 * C57BL/6 * FVB/N	MGI:4365769
cx3	Hey1^tm1Gess/Hey1^tm1Gess Heyl^tm1.2Abmu/Heyl^+	involves: 129 * C57BL/6 * FVB/N	MGI:4365772

Genotype
MGI:4365768

hm1

• Allelic Composition: Heyl^tm1.2Abmu/Heyl^tm1.2Abmu
• Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6 * FVB/N

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

nervous system

decreased sensory neuron number ( J:153555 )

• TrkC+ sensory neurons are reduced 19% in the dorsal root ganglia compared to in wild-type mice

Genotype
MGI:4365769

cx2

• Allelic Composition: Hey1^tm1Gess/Hey1^tm1Gess; Heyl^tm1.2Abmu/Heyl^tm1.2Abmu
• Genetic Background: involves: 129 * C57BL/6 * FVB/N

nervous system

nervous system phenotype ( J:153555 )

N • mice exhibit normal numbers of TrkC+ sensory neurons in the dorsal root ganglia

Genotype
MGI:4365772

cx3

• Allelic Composition: Hey1^tm1Gess/Hey1^tm1Gess; Heyl^tm1.2Abmu/Heyl⁺
• Genetic Background: involves: 129 * C57BL/6 * FVB/N

nervous system

increased sensory neuron number ( J:153555 )

• mice exhibit an increased in the number of TrkC+ sensory neurons in the dorsal root ganglia compared with wild-type mice