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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Mmp10tm1Jkmg
targeted mutation 1, John K McGuire
MGI:4365989
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Mmp10tm1Jkmg/Mmp10tm1Jkmg B6.129X1-Mmp10tm1Jkmg MGI:4365999


Genotype
MGI:4365999
hm1
Allelic
Composition
Mmp10tm1Jkmg/Mmp10tm1Jkmg
Genetic
Background
B6.129X1-Mmp10tm1Jkmg
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mmp10tm1Jkmg mutation (0 available); any Mmp10 mutation (37 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
immune system
• after infection with P. aeruginosa and more severe than in similarly treated wild-type mice
• 4 and 24 hours after infection with Pseudomonas aeruginosa, mice exhibit more severe pulmonary inflammation and pneumonia with extensive hemorrhage and diffuse pulmonary consolidation compared with similarly treated wild-type mice

respiratory system
• after infection with P. aeruginosa unlike similarly treated wild-type mice
• after infection with P. aeruginosa and more severe than in similarly treated wild-type mice

cardiovascular system
• after infection with P. aeruginosa unlike similarly treated wild-type mice





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory