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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Fasltm2.1Ast
targeted mutation 2.1, Andreas Strasser
MGI:4366051
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Fasltm2.1Ast/Fasltm2.1Ast involves: BALB/cJ * C57BL/6 MGI:4366073


Genotype
MGI:4366073
hm1
Allelic
Composition		 Fasltm2.1Ast/Fasltm2.1Ast
Genetic
Background		 involves: BALB/cJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fasltm2.1Ast mutation (0 available); any Fasl mutation (37 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
mortality/aging ( J:153501 )
N
• mice exhibit normal lifespan

immune system
abnormal cytotoxic T cell physiology ( J:153501 )
• T cells are more efficient than wild-type cells at killing CH1 cells

hematopoietic system
abnormal cytotoxic T cell physiology ( J:153501 )
• T cells are more efficient than wild-type cells at killing CH1 cells




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory